The Red Devils have seen off far loftier foes than Olympiakos after first-leg setbacks down the years.
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The Ballon d’Or winner bagging the opener heads our list of the three best Los Blancos bets in Gelsenkirchen.
Committing such a faux pas seems below the meticulous Portuguese, which hints at stage management on his behalf.
The Red Devils have a fantastic pedigree in this competition and virtually all of their big-game players have returned from injury.
The Red Devils primed for a win to nil against a plucky Greek outfit, but it will be hard-fought.