Attrition is on the agenda as these two second-tier heavyweights slug out a low-scoring encounter.
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After a week of frantic debate, the bwinbetting.com brains highlight the best outright bets for the campaign.
Given their stature, Wanderers must be considered good value, while few factions are as formidable as the Royals.
The Reds are set to spark an international net minder relocation programme by selling Pepe Reina to Napoli.
With Arsenal’s top-four finish confirmed, speculation shifts to how they can strengthen to sustain a title challenge next season.
The Championship pair feature in our bank holiday three-way that also sees Elche beat Atletico with a two-goal head start.
Nigel Pearson’s champions elect were battered by Brighton last time out and the Royals can bound back into the play-off places with a win.
The Royals have endured a miserable return to the top flight but their decent record against the Hammers and a recent upturn in form suggest they are a value punt at Upton Park.